GHRH Analogues and GHS-R Ligands

Two receptor families define this category. GHRH analogues are structural derivatives of the 44-residue GHRH sequence; GHS-R1a ligands are short synthetic peptides characterized by binding at the growth hormone secretagogue receptor 1a, a G protein-coupled receptor unrelated in structure to the GHRH receptor.

Tesamorelin is a full-length GHRH(1–44) analogue with an N-terminal trans-3-hexenoyl modification. CJC-1295 (No DAC), also written as modified GRF(1–29), is a tetrasubstituted 29-residue GHRH analogue without the drug-affinity-complex maleimide group. Ipamorelin is a pentapeptide GHS-R1a ligand. The CJC-1295 + ipamorelin product combines one compound from each family in a single vial.

All products are lyophilized, supplied in sealed vials and independently tested for purity by HPLC and identity by mass spectrometry, with certificates published on the product page as testing is completed. For Research Use Only.